By Robert H. Rosa Jr., MD
This quantity is split into elements: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: medical facets. half I makes use of a hierarchy that strikes from common to precise to aid derive a differential prognosis for a particular tissue. half II is a compilation of chosen medical features of value to the overall ophthalmologist. Following half II are the yankee Joint Committee on melanoma 2010 staging kinds for ocular and adnexal tumors. This revised textual content comprises a variety of new pathologic and scientific pictures. significant revision 2011-2012.
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Extra resources for 2011-2012 Basic and Clinical Science Course, Section 4: Ophthalmic Pathology and Intraocular Tumors (Basic & Clinical Science Course)
D, Periodic acid-Sch iff (PASI stain highlights the mucin in goblet cel ls (arrow). E, Caruncul ar conj unctiva, containing sebaceous glands (5) and hair follicles (H). (Parts A-D courtesy of Patricia Chevez-8arrios, MD; part E courtesy of George J. ) episcleral osseous choristoma and osseocartilaginous choristoma complex choristoma Dermoids are finn, dome-shaped, white-yellow papules typically at or straddling the limbus, most commonly in the inferotemporal quadrant (Fig 5-2A, B). They may also in volve the central cornea.
Possible adequacy check during the biopsy (intraocular tumors) ii. Fixative to be used iii. Fresh tissue for possible mo lecula r diagnosi s b. Specific cytology form to be filled out Flow Cytometry 1. Previous communication with ophthalmic pathologist to discuss a. Fresh tissue is critical. b. Adequate samp le is essenti al. c. Geographic proximity to the laboratory Molecu lar Techniqu es and Elect ron M icroscopy 1. Previous communication w ith ophthalmic pathologist to discuss a. Differential diagnosis b.
Bacteria such as Bartonella henselae (cat-scratch disease) and Francisella tularensis (tularemia), mycobacteria (eg, tuberculosis), and trepo nemes (eg, syphiliS) are possible causes. The diagnOSiS can be made by serology, culture, polymerase chain reaction (PCR), or a combi· nation of these. If conjunctival biopsy is performed, the granulomas in in fectious granulomatous conj unctivitis will typically demonstrate central necrosis (caseation). The bacteria may be demo nstrated with Gram, acid· fast, or Warth in-Starry stains, depending on the organism.
2011-2012 Basic and Clinical Science Course, Section 4: Ophthalmic Pathology and Intraocular Tumors (Basic & Clinical Science Course) by Robert H. Rosa Jr., MD